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Exploring a Bioinformatics Clustering Algorithm - Methodology, Experiments, Analysis

Language EnglishEnglish
Book Paperback
Book Exploring a Bioinformatics Clustering Algorithm - Methodology, Experiments, Analysis Mukhlis Matti
Libristo code: 06813024
Publishers VDM Verlag Dr. Mueller E.K., July 2008
Microarray gene expression data are produced around the worldin huge amounts. This data is not easy... Full description
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Microarray gene expression data are produced around the worldin huge amounts. This data is not easy to analyse manually.Therefore, there is a need for automated techniques to do the job.Clustering is one of the automated techniques that can be handed toa computer to cluster the data to groups depending on propertiesthat this data share. An important source of information for suchautomated techniques is the data about genes in large shared textdatabases such as Swiss-Prot. This book explores and evaluatesMAXCCLUS, a bioinformatics clustering algorithm, which clustersgenes from microarray experimental data. MAXCCLUS does theclustering of genes depending on the textual data that describe thegenes. It attempts to create clusters of which it selects only thestatistically significant ones by running a significance test. Itthen attempts to generalise these clusters by using a simple greedygeneralisation algorithm. We explore the behaviour of MAXCCLUS byrunning several clustering experiments that investigate variousmodifications to MAXCCLUS and its data. This book should be usefulto researchers and every one interested in clustering of microarraygene expression data.

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About the book

Full name Exploring a Bioinformatics Clustering Algorithm - Methodology, Experiments, Analysis
Author Mukhlis Matti
Language English
Binding Book - Paperback
Date of issue 2008
Number of pages 172
EAN 9783639033359
ISBN 3639033353
Libristo code 06813024
Weight 236
Dimensions 152 x 229 x 9
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