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Functional Nucleus

Name: Functional Nucleus
Brand: Springer International Publishing AG
SKU: 19771199
Price: 205.74 EUR
Availability: InStock
Author: David P. Bazett-Jones
ISBN: 9783319817682

David P. Bazett-Jones

Graham Dellaire

Language

English

Book Paperback

Libristo code: 19771199

Publishers Springer International Publishing AG, June 2018

This book gives an in-depth overview on nuclear structure and function. It clearly shows that the ep... Full description

Libristo code: 19771199

498 b

205.74 €

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This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.