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Method Development and Validations For Antimalarial Drugs

Name: Method Development and Validations For Antimalarial Drugs
Brand: LAP Lambert Academic Publishing
SKU: 06994228
Price: 79.77 EUR
Availability: InStock
Author: Almustapha Lawal
ISBN: 9783659201820

A Strategy of Method Development and Validations For Antimalarial in Formulations

Almustapha Lawal

Rabiu A. Umar

Mu'azu G. Abubakar

Language

English

Book Paperback

Libristo code: 06994228

Publishers LAP Lambert Academic Publishing, November 2011

Substandard and counterfeit pharmaceutical, especially antimalarials, is a well-recognized and growi... Full description

Libristo code: 06994228

193 b

79.77 €

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Substandard and counterfeit pharmaceutical, especially antimalarials, is a well-recognized and growing public health problem. According to WHO there have been an alarming number of reports of counterfeit antimalarials throughout the world and insufficient regulations and high demand of these very costly pharmaceuticals continues to fuel counterfeiting activity especially in the developing countries. Considering the WHO definition of a counterfeit medicine, in addition, to inadequate resources which mean that there is a scarcity of sophisticated analytical techniques, which hampers the ability to distinguish between genuine and counterfeit drugs. In line with these problems, methods were developed and validated using a reverse phase HPLC method with variable wavelength detector (VWD) for quantification of amodiaquine (AMQ), chloroquine (CQ) and artesunate (ATS) in formulations and spectrophotometric methods using methylene blue and soluble starch as chromogenic agents for Artesunate.