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Myeloid Leukemia

Name: Myeloid Leukemia
Brand: Humana Press Inc.
SKU: 03615948
Price: 100.1 EUR
Availability: InStock
Author: Harry Iland
ISBN: 9781588294852

Methods and Protocols

Harry Iland

Mark Hertzberg

Paula Marlton

Language

English

Book Hardback

Libristo code: 03615948

Publishers Humana Press Inc., November 2005

A panel of internationally recognized research scientists and clinical investigators brings together... Full description

Libristo code: 03615948

244 b

100.10 €

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A panel of internationally recognized research scientists and clinical investigators brings together a diverse collection of readily reproducible methods for identifying and quantifying a large number of specific genetic abnormalities associated with the broad spectrum of myeloid malignancies. Highlights include techniques for the detection of BCR-ABL mutations and resistance to imatinib mesylate, detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia, classification of AML by DNA-oligonucleotide microarrays, and detection of the V617F JAK2 mutation in myeloproliferative disorders. In addition to gene rearrangments, other prognostically relevant molecular lesions such as FLT3 mutations and WT-1 overexpression are covered.