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Large-Scale Optimization with Applications

Name: Large-Scale Optimization with Applications
Brand: Springer-Verlag New York Inc.
SKU: 01385438
Price: 103.1 EUR
Availability: InStock
Author: Lorenz T. Biegler
ISBN: 9780387982885

Lorenz T. Biegler

Thomas Colemann

Andrew R. Conn

Language

English

Book Hardback

Libristo code: 01385438

Publishers Springer-Verlag New York Inc., August 1997

Many important molecular conformation problems, such as protein folding, are expressed as global min... Full description

Libristo code: 01385438

249 b

103.10 €

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Many important molecular conformation problems, such as protein folding, are expressed as global minimization problems. It is the fact that local minimization is insufficient, that markedly differentiates this volume from the previous two. Unfortunately, global minimization problems that result from models of molecular conformation are usually intractable. For example, simple 1-dimensional versions of distance conformation problems are NP-hard. Nevertheless, there has been significant recent progress in the design of promising heuristic strategies (often involving the use of high- performance parallel computers) for computing approximate global minimizers. The purpose of the sessions represented in this volume was to discuss the new algorithmic advances for global minimization in the context of protein folding and related molecular minimization problems. Emphasis was on practical shortcomings of current approaches, outstanding problems and questions, and the use of high-performance parallel computers.